• Aneuploidy prediction and tumor classification with heterogeneous hidden conditional random fields 

      Barutcuoglu, Z; Airoldi, EM; Dumeaux, vanessa; Schapire, RE; Troyanskaya, Olga (Journal article; Tidsskriftartikkel; Peer reviewed, 2009)
      The heterogeneity of cancer cannot always be recognized by tumor morphology, but may be reflected by the underlying genetic aberrations. Array comparative genome hybridization (array-CGH) methods provide high-throughput data on genetic copy numbers, but determining the clinically relevant copy number changes remains a challenge. Conventional classification methods for linking recurrent alterations ...